CD8α mAb (2.43), InVivoPure
The CD8α mAb (2.43) reacts with the 32-34 kDa alpha subunit of mouse CD8, known as CD8a or CD8 alpha.
This antibody is produced exclusively under serum-free conditions from hybridoma and purified with Protein-A or Protein-G affinity chromatography.
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Endotoxin level ≤ 2 EU/mg
The CD8α mAb (2.43) reacts with the 32-34 kDa alpha subunit of mouse CD8, known as CD8a or
CD8 alpha. The CD8α mAb (2.43) is widely used as a phenotypic marker for mouse CD8 on
cytotoxic T cells, thymocytes, as well as on certain cell types that do not also express the TCR,
including some NK cells and lymphoid dendritic cells.
This antibody is produced exclusively under serum-free conditions from hybridoma and
purified with Protein-A or Protein-G affinity chromatography.
| Product-ID: | AK3604P |
|---|---|
| Clone: | 2.43 |
| Immunogen: | Animals were immunized with CTL Clone L3 cells. |
| Host: | Rat |
| Clonality: | Monoclonal |
| Isotype: | IgG2b κ |
| Formulation: | Clear Liquid, PBS, pH 7.4, 0.2 μm sterile filtered |
| Concentration: | ≥ 1.00 mg/mL |
| Purity: | ≥ 90 % (CGE, reducing conditions) |
| ≤ 10 % aggregates (analytical SEC) | |
| Endotoxin: | ≤ 2 EU/mg (LAL test) |
| Storage: | 2 - 8 °C |
The product is for research use or for further manufacturing only and not for use in diagnostic or therapeutic procedures.
The CD8α monoclonal antibody (clone 2.43) was purified from supernatant of TIB-210™ 2.43 from the ATCC. The ATCC trademark and trade name and any and all ATCC catalog numbers are trademarks of the American Type Culture Collection.
Additional information
| Literature | [1] Zamoyska R. The CD8 coreceptor revisited: one chain good, two chains better. Immunity. 1994 Jul;1(4):243-6. |
|---|---|
| Document | |
| Notice | The product is for research use or for further manufacturing only and not for use in diagnostic or therapeutic procedures. |
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