H-2Kd/H-2Dd mAb (34-1-2S), InVivoPure
The anti-H2Kd/H-2Dd monoclonal antibody (clone 34-1-2S) is a mouse-derived antibody that targets MHC class I alloantigens, specifically H-2Kd and H-2Dd. The antibody is critical for antigen presentation to T cells expressing CD3/TCR and CD8 proteins.
This antibody is produced exclusively under serum-free conditions by hybridoma and purified with Protein-A or Protein-G affinity chromatography.
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Endotoxin level ≤ 2 EU/mg
The anti-H2Kd/H-2Dd monoclonal antibody (clone 34-1-2S) is a mouse-derived antibody that targets MHC class I alloantigens, specifically H-2Kd and H-2Dd. These antigens are expressed on the surface of nucleated cells in mice with the H-2Kd/H-2Dd haplotype. The antibody is critical for antigen presentation to T cells expressing CD3/TCR and CD8 proteins.
This antibody is known for its cross-reactivity with other MHC class I alloantigens, including those of the H-2Kb, H-2Ks, H-2Kr, H-2Kq, and H-2Kp haplotypes. It is commonly used in flow cytometry for the analysis of mouse splenocytes and other cell types.
This antibody is a valuable tool for researchers studying immune responses by helping to identify and characterize cells based on their MHC class I expression.
This antibody is produced exclusively under serum-free conditions by hybridoma and purified by Protein-A or Protein-G affinity chromatography.
Product-ID: | AK3642P |
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Clone: | 34-1-2S |
Immunogen: | Animals were immunized with spleen cells from BDF1 mice |
Host: | Mouse |
Clonality: | Monoclonal |
Isotype: | Mouse IgG2a |
Formulation: | Clear Liquid, PBS, pH 7.4, 0.2 μm sterile filtered |
Concentration: | ≥ 1.00 mg/mL |
Purity: | ≥ 90 % (CGE, reducing conditions) |
≤ 10 % aggregates (analytical SEC) | |
Endotoxin: | ≤ 2 EU/mg (LAL test) |
Storage: | 2 - 8 °C |
Recommended Isotype Control: | Mouse IgG2a ĸ Isotype Control (AK3399P) |
The product is for research use only and not for use in diagnostic or therapeutic procedures.
The anti-H2Kd/H-2Dd monoclonal antibody (clone 34-1-2S) was purified from supernatant of HB-79™ 34-1-2S from the ATCC. The ATCC trademark and trade name and any and all ATCC catalog numbers are trademarks of the American Type Culture Collection.
Additional information
Literature | [1] Tryphonas M, King DP, Jones PP. Identification of a second class I antigen controlled by the K end of the H-2 |
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Document | |
Notice | The product is for research use only and not for use in diagnostic or therapeutic procedures. |
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